i don't really recommend makeup remover for big fluffy powder/blush brushes. most makeup removers have oils and if left unwashed, it may affect the way the bristles "grab" or "release" powders. for smaller brushes with synthetic bristles (usually lip and concealer brushes) where sticky products were used, a little makeup remover or cosmetic brush cleaner dabbed unto soft cloth or tissue will help remove stubborn products. gently swirl the brush taking care not to bend the bristles too much.